Arizona Cardinals @ San Francisco 49ers

Arizona CardinalsCardinalsARI

0-0, 0-0 Away

San Francisco 49ers49ersSF

0-0, 0-0 Home

Injury Report

Arizona Cardinals

Name	Status	Est. Return
Josh SweatJ. SweatLB	PUP-PKnee	Aug 6
Joey BlountJ. BlountS	QuestionableUndisclosed	Aug 6
Valentin SennV. SennOT	QuestionableUndisclosed	Aug 6
James ConnerJ. ConnerRB	QuestionableFoot	Aug 6
Kaleb ProctorK. ProctorDT	IRKnee - Meniscus	Feb 15

San Francisco 49ers

Name	Status	Est. Return
Nick BosaN. BosaDE	QuestionableKnee - ACL	Aug 13
Mike EvansM. EvansWR	QuestionableQuadriceps	Aug 13
George KittleG. KittleTE	PUP-PAchilles	Sep 10
Christian KirkC. KirkWR	QuestionableCalf	Aug 13
De'Zhaun StriblingD. StriblingWR	QuestionableHamstring	Aug 13

Cardinals

DATE	OPP	RESULT
8/6/26	vsCAR	L33-30
1/4/26	@LAR	L37-20
12/28/25	@CIN	L37-14
12/21/25	vsATL	L26-19
12/14/25	@HOU	L40-20

49ers

DATE	OPP	RESULT
1/17/26	@SEA	L41-6
1/11/26	@PHI	W23-19
1/3/26	vsSEA	L13-3
12/28/25	vsCHI	W42-38
12/22/25	@IND	W48-27

Data is currently unavailable.

2026-09-27T20:05ZOpenSpreadTotalML

Arizona CardinalsCardinalsARI

(0-0)

(0-0, 0-0 Away)

o46.5

-110

San Francisco 49ers49ersSF

(0-0)

(0-0, 0-0 Home)

-11.5

-110

49ers vs CardinalsLevi's Stadium - Sun 9/27/26, 4:05Tickets as low as $101

Buy 49ers tickets with VividSeats

National Football Conference

NFC West	L	PCT	PF	PA
Los Angeles	0	.000	0	0
San Francisco	0	.000	0	0
Seattle	0	.000	0	0
Arizona	1	.000	30	33

NFL News

Schefter: Cowboys remain most valuable sports franchise at $15.5 billion

Fantasy football buzz: More volume for Chase Brown, Denzel Boston turning heads

Cameron Wolfe details his latest camp trip to Ohio, with the biggest buzz from the Bengals and Browns.

Riddick: If Pats can answer edge question, they'll be in AFC title game

GAMBLING PROBLEM? CALL 1-800-GAMBLER or 1-800-MY-RESET, (800) 327-5050 or visit gamblinghelplinema.org (MA). Call 877-8-HOPENY/text HOPENY (467369) (NY). Call 888-789-7777/visit ccpg.org (CT), or visit www.mdgamblinghelp.org (MD), 1-800-981-0023 (PR). 21+ and present in most states. (18+ DC/KY/NH/PR/WY). Void in ONT. Eligibility restrictions apply. Terms: draftkings.com/sportsbook. On behalf of Boot Hill Casino (KS). Pass-thru of per wager tax may apply in IL.