NFL Week 10 betting odds: Lines and totals for every game

Brock Purdy and the 49ers visit the Cowboys in Week 10 in what is projected to be a high-scoring affair. AP Photo/Kelley L. Cox

Week 10 got underway with the Washington Commanders defeating the NFC East-leading New York Giants 24-21 on Thursday to tighten the division race.

NFL action resumes Sunday morning with New England Patriots and Detroit Lions meeting in Munich, where the Lions are 2.5-point favorites. The Jacksonville Jaguars are the biggest favorites of the week, laying 10.5 points Sunday afternoon on the road against the Tennessee Titans. The San Francisco 49ers-Dallas Cowboys matchup in the late afternoon window has the highest total (55.5).

The winless Los Angeles Chargers will visit the Baltimore Ravens on "Monday Night Football" (8:15 p.m. ET on ESPN) to close out the week.

The Chicago Bears, Denver Broncos, Philadelphia Eagles and Tampa Bay Buccaneers are on byes. Here's a look at the odds for every game this week. (You can find our early bets for Week 10 here.)

Note: Odds by DraftKings and subject to change. All times Eastern.

Jump to:
WSH-NYG | NE-DET | BUF-NYJ | KC-ATL
MIA-IND | JAX-TEN | MIN-GB | CAR-NO
HOU-CLE | LAR-ARI | SEA-LV | SF-DAL
PIT-CIN | LAC-BAL


New England Patriots vs. Detroit Lions -2.5
Sunday, 9:30 a.m., Fox


Moneyline: Patriots (+124); Lions (-148)
Total: 49.5; Opened: 48.5
FPI favorite: Lions by 0.7 with a 53% probability to win the game outright


Buffalo Bills -8.5 vs. New York Jets
Sunday, 1 p.m., CBS


Moneyline: Bills (-425); Jets (+330)
Total: 50.5; Opened: 46.5
FPI favorite: Bills by 9.4 with a 83% probability to win the game outright


Check out the latest Super Bowl odds and major NFL awards futures.


Kansas City Chiefs -3 vs. Atlanta Falcons
Sunday, 1 p.m., CBS


Moneyline: Chiefs (-185); Falcons (+154)
Total: 47.5; Opened: 45.5
FPI favorite: Chiefs by 7.8 with a 78% probability to win the game outright


Miami Dolphins vs. Indianapolis Colts -3.5
Sunday, 1 p.m., CBS


Moneyline: Dolphins (+170); Colts (-205)
Total: 38.5; Opened: 47.5
FPI favorite: Colts by 9.2 with a 82% probability to win the game outright


Jacksonville Jaguars -10.5 vs. Tennessee Titans
Sunday, 1 p.m., Fox


Moneyline: Jaguars (-650); Titans (+470)
Total: 46.5; Opened: 45.5
FPI favorite: Jaguars by 10.1 with a 84% probability to win the game outright


Minnesota Vikings vs. Green Bay Packers -3
Sunday, 1 p.m., Fox


Moneyline: Vikings (+130); Packers (-155)
Total: 41.5; Opened: 45.5
FPI favorite: Packers by 1.3 with a 55% probability to win the game outright


Carolina Panthers vs. New Orleans Saints -2.5
Sunday, 1 p.m., Fox


Moneyline: Panthers (+114); Saints (-135)
Total: 48.5; Opened: 43.5
FPI favorite: Panthers by 0 with a 50% probability to win the game outright


Houston Texans -4.5 vs. Cleveland Browns
Sunday, 1 p.m., Fox


Moneyline: Texans (-238); Browns (+195)
Total: 40.5; Opened: 38.5
FPI favorite: Texans by 7.2 with a 77% probability to win the game outright


Los Angeles Rams -9.5 vs. Arizona Cardinals
Sunday, 4:05 p.m., CBS


Moneyline: Rams (-500); Cardinals (+380)
Total: 39.5; Opened: 47.5
FPI favorite: Rams by 11.4 with a 87% probability to win the game outright


Seattle Seahawks -6.5 vs. Las Vegas Raiders
Sunday, 4:05 p.m., CBS


Moneyline: Seahawks (-298); Raiders (+240)
Total: 40.5; Opened: 43.5
FPI favorite: Seahawks by 6.4 with a 74% probability to win the game outright


San Francisco 49ers -3.5 vs. Dallas Cowboys
Sunday, 4:25 p.m., Fox


Moneyline: 49ers (-205); Cowboys (+170)
Total: 55.5; Opened: 52.5
FPI favorite: 49ers by 3.5 with a 64% probability to win the game outright


Pittsburgh Steelers vs. Cincinnati Bengals -3.5
Sunday, 8:20 p.m., NBC


Moneyline: Steelers (+150); Bengals (-180)
Total: 49.5; Opened: 47.5
FPI favorite: Bengals by 5.4 with a 71% probability to win the game outright


Los Angeles Chargers vs. Baltimore Ravens -4.5
Monday, 8:15 p.m., ESPN


Moneyline: Chargers (+180); Ravens (-218)
Total: 38.5; Opened: 48.5
FPI favorite: Chargers by 1.2 with a 55% probability to win the game outright

Thursday's result


Washington Commanders vs. New York Giants -1.5 (40.5)
Commanders 24, Giants 21