As boos rang out last week at Crystal Palace and Nottingham Forest, a dismal run of first legs for Premier League sides in Europe came to a close.
Nine English sides were in action, with only one coming out on top, Aston Villa beating Lille 1-0.
Elsewhere, across the Champions League, Europa League and Conference League, three English side managed to secure draws. The other five all fell to defeat.
With second legs fast approaching, what can Premier League sides do this week to turn around their fortunes and keep their European hopes alive?
Champions League
Of the English Champions League sides, Arsenal have the best chance of reaching the quarterfinals according to Opta.
Kai Havertz's late penalty away to Bayer Leverkusen levelled that tie at 1-1 after first leg, leaving Mikel Arteta and co with a 78.1% chance of winning at home at the Emirates on Tuesday.
Liverpool have a 51.4% chance joining them in the quarterfinals, again according to Opta. After travelling to Istanbul to take on Galatasaray last week, Arne Slot's group are down 1-0 heading back to Anfield.
Newcastle are level in their tie with Barcelona - Lamine Yamal's late penalty cancelling out Harvey Barnes' opener at St James' Park. They are, though, up against it on their travels in the second leg.
The stattos give Eddie Howe's team a 31.9% chance of progressing, lower than Liverpool even though Newcastle don't currently trail in the tie.
- Arsenal are making football worse, despite Dowman's dream moment
- Leonard Prescott, 16, in line for Bayern Munich debut after third goalkeeper injured
- Jude Bellingham, Kylian Mbappé back in Real Madrid's Champions League squad
Tottenham, Chelsea and Manchester City are all staring at early European exits thanks to three-goal first leg deficits.
Spurs lost 5-2 away to Atlético Madrid in a game remembered for Igor Tudor's decision to haul off goalkeeper Antonín Kinsky inside 15 minutes.
Federico Valverde's hat-trick gave Real Madrid a 3-0 victory over Manchester City while PSG also beat Chelsea 5-2.
All three English sides are at home in the second leg, perhaps offering some hope of manufacturing a remarkable turnaround.
Round-of-16 second legs:
Arsenal (1) vs. (1) Bayer Leverkusen
Chelsea (2) vs. (5) PSG
Man City (0) vs. (3) Real Madrid
Barcelona (1) vs. (1) Newcastle
Tottenham (2) vs. (5) Atlético Madrid
Europa League
The only English team currently ahead in their tie is Aston Villa.
Ollie Watkins ensured Unai Emery's side took a 1-0 lead away from Lille last week, meaning avoiding defeat in Villa Park on Thursday will see them progress.
Nottingham Forest have to overturn a 1-0 deficit when travelling to Denmark to take on Midtjylland in their second leg.
Round-of-16 second legs:
Aston Villa (1) vs. (0) Lille
Midtjylland (1) vs. (0) Nottingham Forest
Conference League
Crystal Palace are also away from home, their tie with Cypriot side AEK Larnaca delicately poised at 0-0.
Round-of-16 second leg:
AEK Larnaca (0) vs. (0) Crystal Palace
What's been said?
Unai Emery for one was quick to point out his side's bucking of the trend this week.
"We respect this competition because we know the difficulties of each match in Europe, away, and how it is for the English teams, like yesterday in the Champions League, how they were struggling," said the Villa boss after his side won away from home.
Meanwhile Arne Slot warned against jumping to early conclusions regarding the strength of the Premier League sides compared to their European rivals.
"To jump to a conclusion after one game day, I think that is such a small sample size that is never the smartest thing to do because maybe, after next week, we will have a different conclusion," said the Dutchman.
"In general, I think it is not helpful for English clubs not to have a winter break, but I am not saying that all these teams have lost because we don't have a winter break.
"You are facing in the last-16 of Europe good teams and four of the five teams in the Champions League played away from home. It is usually an advantage to play at home and a disadvantage to play away.
"To jump to conclusions -- missing a winter break or the level of the Premier League is not as high as we expected it to be -- would be, for me, at this moment in time, not the right conclusion to make.
"Let's first judge us all after next week and then maybe it is still too early to jump to conclusions."
