The Women's Six Nations returns after the fallow week with England travelling to Parma to face Italy in Round 4.
Despite several personnel disruptions, the Red Roses have made a strong start to the competition and lead the standings with maximum bonus points.
Italy meanwhile are third following their win over Scotland in Round 3.
Here is everything you need to know ahead of this week's clash.
Key details:
Who: Italy vs. England
When: Saturday, May 9 at 2 p.m. BST [3 p.m. local time]
Where: Stadio Sergio Lanfranchi, Parma
Referee: Jess Ling (RA)
Assistant referees: Robbie Jenkinson (IRFU), Berenice Loubet (FFR)
Television Match Official: Leo Colgan (IRFU)
Where is Italy vs. England being broadcast?
The BBC will broadcast the game in the UK while BBC Radio 5 Live will have audio commentary.
Team news:
England have been dealt another forward injury blow after number eight Alex Matthews was ruled out of the final two matches of the Guinness Women's Six Nations.
The double World Cup winner is to undergo surgery this week on the shoulder damage sustained in the 33-12 victory over Ireland in round one, preventing her from facing Italy on Saturday or France in the likely title decider a week later.
Lilli Ives Campion and Sadia Kabeya are continuing their rehab in camp in the hope of being available for the visit to Bordeaux on May 17, while Hannah Botterman and Morwenna Talling are also in the treatment room.
Furthermore, Zoe Stratford, Abbie Ward, Lark Atkin-Davies and Rosie Galligan are missing due to pregnancy.
Information from PA was used in this report.