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    Denver Broncos @ San Francisco 49ers

    DEN
    Denver BroncosBroncosDEN
    2-1, 0-1 Away
    SF
    San Francisco 49ers49ersSF
    3-0, 2-0 Home
    • Gamecast
    • Odds
    • TicketsExternal Link

    Game Odds
    Odds by

    2026-10-04T20:25ZOpenSpreadTotalML
    Denver BroncosDenver BroncosDEN
    (2-1)
    (2-1)
    o46.5
    -110
    +3
    -120
    o47.5
    -110
    +124
    San Francisco 49ersSan Francisco 49ersSF
    (3-0)
    (3-0)
    -2.5
    -110
    -3
    +100
    u47.5
    -110
    -148
    See More Odds

    Recent Schedule

    DATEOPPRESULTSPREADTOTAL
    9/27vsLARW30-26-1.544.5
    9/20vsJAXW20-13-2.545.5
    9/14@KCL31-10+2.542.5
    8/28vsMINW34-6-4.537.5
    8/21vsGBL33-13-6.540.5

    Matchup Predictor

    Denver Broncos
    San Francisco 49ers
    22.8
    %

    DEN

    77.0
    %

    SF

    According to ESPN Analytics

    Betting 101

    The Beginner's Guide to BettingReady to enter the world of sports betting? Here's everything you need to know to get started.
    Christian McCaffrey
    SF RB
    J.K. Dobbins
    DEN RB
    George Kittle
    SF TE
    Mike Evans
    SF WR
    Deebo Samuel Sr.
    SF WR
    RJ Harvey
    DEN RB
    Jaylen Waddle
    DEN WR
    Courtland Sutton
    DEN WR
    FIRST TD
    Anytime TD
    2+ TDs
    +380
    -215
    +265
    +650
    +120
    +800
    +1000
    +160
    +1200
    +1100
    +175
    +1300
    +1100
    +180
    +1300
    +1300
    +225
    +2000
    +1300
    +215
    +1900
    +1400
    +220
    +1900
    See More Odds
    Bo Nix
    DEN QB
    26+
    28+
    30+
    32+
    34+
    35+
    36+
    +104
    38+
    40+
    42+
    44+
    46+
    48+
    Brock Purdy
    SF QB
    24+
    26+
    28+
    30+
    32+
    -104
    34+
    36+
    38+
    40+
    42+
    44+
    See More Odds
    Brock Purdy
    SF QB
    Bo Nix
    DEN QB
    o234.5
    -111
    u234.5
    -113
    o225.5
    -112
    u225.5
    -112
    See More Odds
    Christian McCaffrey
    SF RB
    J.K. Dobbins
    DEN RB
    Kaelon Black
    SF RB
    Bo Nix
    DEN QB
    o64.5
    -113
    u64.5
    -111
    o61.5
    -112
    u61.5
    -112
    o22.5
    -113
    u22.5
    -111
    o19.5
    -116
    u19.5
    -108
    See More Odds
    George Kittle
    SF TE
    Jaylen Waddle
    DEN WR
    Christian McCaffrey
    SF RB
    Courtland Sutton
    DEN WR
    Pat Bryant
    DEN WR
    RJ Harvey
    DEN RB
    o64.5
    -110
    u64.5
    -114
    o57.5
    -110
    u57.5
    -114
    o39.5
    -109
    u39.5
    -115
    o37.5
    -112
    u37.5
    -112
    o23.5
    -113
    u23.5
    -111
    o22.5
    -109
    u22.5
    -115
    See More Odds
    San Francisco 49ers
    3-0
    Denver Broncos
    2-1
    o15.5
    -800
    u15.5
    +550
    o12.5
    -1000
    u12.5
    +650
    See More Odds

    Injury Report

    Denver Broncos
    NameStatus
    Jaylen WaddleJ. WaddleWR
    QuestionableLeg
    Marvin Mims Jr.M. Mims Jr.WR
    QuestionableFoot
    Jonathon CooperJ. CooperLB
    Reserve-CelPersonal
    Nick GargiuloN. GargiuloG
    PUP-RKnee - ACL
    Frank CrumF. CrumOT
    IR-RUndisclosed
    San Francisco 49ers
    NameStatus
    Romello HeightR. HeightDE
    QuestionableHand
    Mike EvansM. EvansWR
    QuestionableRibs
    Dre GreenlawD. GreenlawLB
    QuestionableQuadriceps
    Gracen HaltonG. HaltonDT
    QuestionableAnkle
    Trent WilliamsT. WilliamsOT
    QuestionableNeck
    Full Injury Report

    Super Bowl Winner

    TEAMODDS
    LARLAR+670
    BUFBUF+670
    BALBAL+900
    SFSF+900
    SEASEA+1000
    KCKC+1050
    PHIPHI+1700
    CINCIN+1700
    TEAMODDS
    DETDET+1900
    DENDEN+2000
    JAXJAX+2200
    NENE+2400
    CHICHI+2400
    MINMIN+2400
    DALDAL+2800
    HOUHOU+3500
    See More NFL Futures
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